CEACAM16 gene

carcinoembryonic antigen related cell adhesion molecule 16

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non-syndromic autosomal dominant hearing loss. [provided by RefSeq, May 2012]

From UniProt:

Required for proper hearing, it may play a role in maintaining the integrity of the tectorial membrane.

Covered on Genetics Home Reference:

From NCBI Gene:

  • Deafness, autosomal dominant 4b

From UniProt:

Deafness, autosomal dominant, 4B (DFNA4B): A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. [MIM:614614]

Cytogenetic Location: 19q13.31-q13.32, which is the long (q) arm of chromosome 19 between positions 13.31 and 13.32

Molecular Location: base pairs 44,699,151 to 44,710,714 on chromosome 19 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 19q13.31-q13.32, which is the long (q) arm of chromosome 19 between positions 13.31 and 13.32
  • CEAL2
  • DFNA4B