CD58

CD58 molecule

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]

From UniProt:

Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Cytogenetic Location: 1p13, which is the short (p) arm of chromosome 1 at position 13

Molecular Location: base pairs 116,487,140 to 116,571,093 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1p13, which is the short (p) arm of chromosome 1 at position 13
  • ag3
  • LFA-3
  • LFA3