CCR6

C-C motif chemokine receptor 6

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

From UniProt:

Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

Cytogenetic Location: 6q27, which is the long (q) arm of chromosome 6 at position 27

Molecular Location: base pairs 167,111,807 to 167,139,141 on chromosome 6 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 6q27, which is the long (q) arm of chromosome 6 at position 27
  • BN-1
  • C-C CKR-6
  • CC-CKR-6
  • CCR-6
  • CD196
  • CKR-L3
  • CKRL3
  • CMKBR6
  • DCR2
  • DRY6
  • GPR29
  • GPRCY4
  • STRL22