CARTPT gene

CART prepropeptide

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016]

From UniProt:

Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro.

Cytogenetic Location: 5q13.2, which is the long (q) arm of chromosome 5 at position 13.2

Molecular Location: base pairs 71,719,163 to 71,721,048 on chromosome 5 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 5q13.2, which is the long (q) arm of chromosome 5 at position 13.2