CALU gene

calumenin

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

From UniProt:

Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.

Cytogenetic Location: 7q32.1, which is the long (q) arm of chromosome 7 at position 32.1

Molecular Location: base pairs 128,739,292 to 128,773,423 on chromosome 7 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 7q32.1, which is the long (q) arm of chromosome 7 at position 32.1