CALCR gene

calcitonin receptor

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

From UniProt:

This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

Cytogenetic Location: 7q21.3, which is the long (q) arm of chromosome 7 at position 21.3

Molecular Location: base pairs 93,424,487 to 93,574,730 on chromosome 7 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 7q21.3, which is the long (q) arm of chromosome 7 at position 21.3
  • CRT
  • CT-R
  • CTR
  • CTR1