C7 gene

complement C7

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008]

From UniProt:

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.

From NCBI Gene:

  • Complement component 7 deficiency

From UniProt:

Complement component 7 deficiency (C7D): A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. [MIM:610102]

Cytogenetic Location: 5p13.1, which is the short (p) arm of chromosome 5 at position 13.1

Molecular Location: base pairs 40,909,497 to 40,982,939 on chromosome 5 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 5p13.1, which is the short (p) arm of chromosome 5 at position 13.1