AUTS2 gene

autism susceptibility candidate 2

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2014]

From NCBI Gene:

  • Mental retardation, autosomal dominant 26

From UniProt:

Mental retardation, autosomal dominant 26 (MRD26): A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Additional MRD26 features include autism, short stature, microcephaly, cerebral palsy, and facial dysmorphisms. [MIM:615834]

Cytogenetic Location: 7q11.22, which is the long (q) arm of chromosome 7 at position 11.22

Molecular Location: base pairs 69,598,475 to 70,793,068 on chromosome 7 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 7q11.22, which is the long (q) arm of chromosome 7 at position 11.22
  • FBRSL2
  • MRD26