ATP6AP1 gene

ATPase H+ transporting accessory protein 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]

From UniProt:

Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Cytogenetic Location: Xq28, which is the long (q) arm of the X chromosome at position 28

Molecular Location: base pairs 154,428,632 to 154,436,517 on the X chromosome (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: Xq28, which is the long (q) arm of the X chromosome at position 28
  • 16A
  • Ac45
  • ATP6IP1
  • ATP6S1
  • CF2
  • VATPS1
  • XAP-3
  • XAP3