ARL11 gene

ADP ribosylation factor like GTPase 11

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010]

From UniProt:

May play a role in apoptosis. May act as a tumor suppressor.

From UniProt:

Leukemia, chronic lymphocytic (CLL): A chronic leukemia in which functionally incompetent B-lymphocytes progressively accumulate in the bone marrow, blood, and lymphoid tissues. The clinical evolution of the disorder is heterogeneous, with some patients having indolent disease and others having aggressive disease and short survival. [MIM:151400]

Cytogenetic Location: 13q14.2, which is the long (q) arm of chromosome 13 at position 14.2

Molecular Location: base pairs 49,628,299 to 49,633,872 on chromosome 13 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 13q14.2, which is the long (q) arm of chromosome 13 at position 14.2
  • ARLTS1