ARHGAP20 gene

Rho GTPase activating protein 20

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016]

From UniProt:

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.

From UniProt:

A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL) (PubMed:15543602). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes (PubMed:15543602).

Cytogenetic Location: 11q22.3-q23.1, which is the long (q) arm of chromosome 11 between positions 22.3 and 23.1

Molecular Location: base pairs 110,577,035 to 110,713,189 on chromosome 11 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 11q22.3-q23.1, which is the long (q) arm of chromosome 11 between positions 22.3 and 23.1
  • RARHOGAP