AQP7 gene

aquaporin 7

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015]

From UniProt:

Forms a channel for water and glycerol.

From NCBI Gene:

  • Glycerol release during exercise, defective

Cytogenetic Location: 9p13, which is the short (p) arm of chromosome 9 at position 13

Molecular Location: base pairs 33,383,135 to 33,402,682 on chromosome 9 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 9p13, which is the short (p) arm of chromosome 9 at position 13
  • AQP7L
  • AQPap
  • GLYCQTL