ALG10 gene

ALG10, alpha-1,2-glucosyltransferase

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. [provided by RefSeq, Jan 2010]

From UniProt:

Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.

Cytogenetic Location: 12p11.1, which is the short (p) arm of chromosome 12 at position 11.1

Molecular Location: base pairs 34,022,281 to 34,028,302 on chromosome 12 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 12p11.1, which is the short (p) arm of chromosome 12 at position 11.1
  • ALG10A
  • DIE2
  • KCR1