AHSG gene

alpha 2-HS glycoprotein

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several processes, including endocytosis, brain development, and the formation of bone tissue. Defects in this gene are a cause of susceptibility to leanness. [provided by RefSeq, Aug 2017]

From UniProt:

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

From NCBI Gene:

  • Alopecia mental retardation syndrome 1

From UniProt:

Alopecia-mental retardation syndrome 1 (APMR1): A rare autosomal recessive form of alopecia. APMR1 patients show loss of hair on the scalp, absence of eyebrows, eyelashes, axillary and pubic hair, and mild to severe mental retardation. [MIM:203650]

Cytogenetic Location: 3q27.3, which is the long (q) arm of chromosome 3 at position 27.3

Molecular Location: base pairs 186,612,923 to 186,621,318 on chromosome 3 (Homo sapiens Annotation Release 109, GRCh38.p12) (NCBI)

Cytogenetic Location: 3q27.3, which is the long (q) arm of chromosome 3 at position 27.3
  • A2HS
  • AHS
  • APMR1
  • FETUA
  • HSGA