ADRB1 gene

adrenoceptor beta 1

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]

From UniProt:

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.

Cytogenetic Location: 10q25.3, which is the long (q) arm of chromosome 10 at position 25.3

Molecular Location: base pairs 114,044,047 to 114,046,908 on chromosome 10 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 10q25.3, which is the long (q) arm of chromosome 10 at position 25.3
  • ADRB1R
  • B1AR
  • BETA1AR
  • RHR