ADAM29 gene

ADAM metallopeptidase domain 29

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

From UniProt:

May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein.

From UniProt:

Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.

Cytogenetic Location: 4q34, which is the long (q) arm of chromosome 4 at position 34

Molecular Location: base pairs 174,918,358 to 174,978,180 on chromosome 4 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 4q34, which is the long (q) arm of chromosome 4 at position 34
  • CT73
  • svph1