ACP6 gene

acid phosphatase 6, lysophosphatidic

The information on this page was automatically extracted from online scientific databases.

From NCBI Gene:

This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016]

From UniProt:

Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.

Cytogenetic Location: 1q21, which is the long (q) arm of chromosome 1 at position 21

Molecular Location: base pairs 147,629,658 to 147,670,543 on chromosome 1 (Homo sapiens Annotation Release 108, GRCh38.p7) (NCBI)

Cytogenetic Location: 1q21, which is the long (q) arm of chromosome 1 at position 21
  • ACPL1
  • LPAP
  • PACPL1