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Structural changes to chromosomes
Inversions occur when a chromosome breaks in two places and the resulting piece of DNA is reversed and re-inserted into the chromosome.  Inversions that involve the centromere are called pericentric inversions; those that do not involve the centromere are called paracentric inversions.

Inversions occur when a chromosome breaks in two places and the resulting piece of DNA is reversed and re-inserted into the chromosome. Inversions that involve the centromere are called pericentric inversions; those that do not involve the centromere are called paracentric inversions.