segment at the end of each chromosome arm which consists of a series of repeated
DNA sequences that regulate chromosomal replication at each cell division.
Some of the telomere is lost each time a cell divides, and eventually, when
the telomere is gone, the cell dies.
Definition from: GeneReviews
from the University of Washington and the National Center for Biotechnology Information
- The natural end of a eukaryotic chromosome composed of a usually repetitive DNA sequence and serving to stabilize the chromosome.
Definition from: Merriam-Webster's Medical Dictionary by Merriam-Webster Inc.
- A telomere is the end of a chromosome. Telomeres are made of repetitive sequences of non-coding DNA that protect the chromosome from damage. Each time a cell divides, the telomeres become shorter. Eventually, the telomeres become so short that the cell can no longer divide.
Definition from: Talking Glossary of Genetic Terms from the National Human Genome Research Institute
Related discussion in the Handbook
See also Understanding Medical Terminology.