- A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.
Definition from: MeSH via Unified Medical Language System at the National Library of Medicine
- 1: A pathological condition in which a tissue has become hard and which is produced by overgrowth of fibrous tissue and other changes (as in arteriosclerosis) or by increase in interstitial tissue and other changes (as in multiple sclerosis) -- called also hardening.
2: Any of various diseases characterized by sclerosis -- usually used in combination.
Definition from: Merriam-Webster's Medical Dictionary by Merriam-Webster Inc.
Related discussion in the Handbook
See also Understanding Medical Terminology.