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Neurofibrillary tangles


  • Alzheimer's neurofibrillary change
  • Alzheimer's neurofibrillary degeneration
  • argentophilic neuronal inclusion
  • NFT


A pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of nerve cells of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease.

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

See also Understanding Medical Terminology.

Published: February 8, 2016