- A neoplasm that arises from Schwann cells of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)
Definition from: MeSH via Unified Medical Language System at the National Library of Medicine
- A tumor of the peripheral nervous system composed of neoplastic Schwann cells. The vast majority of Schwannomas follow a benign clinical course. Only rare cases associated with a malignant clinical course have been reported. -- 2004
Definition from: NCI Thesaurus via Unified Medical Language System at the National Library of Medicine
- A tumor of the peripheral nervous system that arises in the nerve sheath (protective covering). It is almost always benign, but rare malignant schwannomas have been reported.
National Cancer Institute
See also Understanding Medical Terminology.