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Neural tube defects

Synonym(s)

  • NTD - neural tube defect

Definition(s)

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)

Definition from: MeSH via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

Any of various congenital defects (as anencephaly and spina bifida) caused by incomplete closure of the neural tube during the early stages of embryonic development.

Definition from: Merriam-Webster's Medical DictionaryThis link leads to a site outside Genetics Home Reference. by Merriam-Webster Inc.

See also Understanding Medical Terminology.

 
Published: May 21, 2012