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Microsatellite instability

Definition(s)

(MSI) The presence of additional microsatellite alleles (repeated segments) in tumor cells, resulting from the inherent susceptibility of these areas to such alterations and from mutations in the DNA mismatch repair mechanism that would normally correct these errors

Definition from: GeneReviewsThis link leads to a site outside Genetics Home Reference. from the University of Washington and the National Center for Biotechnology Information

See also Understanding Medical Terminology.

 
Published: March 23, 2015