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Metalloprotease

Synonym(s)

  • metallopeptidases
  • metalloproteinases

Definition(s)

Proteases which use a metal, normally zinc, in the catalytic mechanism. This group of enzymes is inactivated by metal chelators.

Definition from: MeSH via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

Encoded by metalloproteinase genes, metalloproteinases (endopeptidases) use a metal ion, normally zinc, in the catalytic process and preferentially cleave the Gln-Gly peptide bond. Metalloproteinases inactivated by metal chelators.

Definition from: NCI Thesaurus via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

See also Understanding Medical Terminology.

 
Published: July 27, 2015