- A haplotype is a set of DNA variations, or polymorphisms, that tend to be inherited together. A haplotype can refer to a combination of alleles or to a set of single nucleotide polymorphisms (SNPs) found on the same chromosome. Information about haplotypes is being collected by the International HapMap Project and is used to investigate the influence of genes on disease.
Definition from: Talking Glossary of Genetic Terms from the National Human Genome Research Institute
- A group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit.
Definition from: Merriam-Webster's Medical Dictionary by Merriam-Webster Inc.
Related discussion in the Handbook
See also Understanding Medical Terminology.