- blood coagulation factor I
- coagulation factor I
- factor I
- A fibrillar protein present in blood plasma; it converts to fibrin during the process of blood clot formation.
Definition from: NCI via Unified Medical Language System at the National Library of Medicine
- Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Definition from: MeSH via Unified Medical Language System at the National Library of Medicine
Related discussion in the Handbook
See also Understanding Medical Terminology.