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Exon scanning


The process by which certain exons (coding regions within a gene), under highest suspicion to contain a specific mutation, are subjected to testing via conformation sensitive gel electrophoresis (CSGE), single-stranded conformational-polymorphism (SSCP), denaturing gradient gel electrophoresis (DGGE), or other means deemed most appropriate, to confirm the presence of a mutation before use of further testing, such as sequencing, to delineate the exact nature of the mutation; used to expedite analysis when the disorder in question can be caused by numerous possible mutations within a gene

Definition from: GeneReviewsThis link leads to a site outside Genetics Home Reference. from the University of Washington and the National Center for Biotechnology Information

See also Understanding Medical Terminology.

Published: February 1, 2016