Identification of mutations by electrophoresis of double-stranded DNA samples
through a denaturing gradient, such as urea. Certain mutations affect the
migration pattern by changing the point in the gel at which the DNA denatures;
mutant sequences can be distinguished from wild-type sequences by comparing
the electrophoretic pattern.
Definition from: GeneReviews
from the University of Washington and the National Center for Biotechnology Information
See also Understanding Medical Terminology.