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Chromatin remodeling

Synonym(s)

  • chromatin modelling

Definition(s)

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. [GOC:jic, PMID:12697820]

Definition from: Gene Ontology via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

Chromatin Remodeling involves alterations of the content or activity of DNA-binding and chromatin-associated proteins that affect the function and higher order conformational state of chromatin, as well as the activity of specific genes or functional DNA regions.

Definition from: NCI Thesaurus via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

The mechanisms involved with making the DNA in CHROMATIN more or less accessible to transcription machinery.

Definition from: MeSH via Unified Medical Language SystemThis link leads to a site outside Genetics Home Reference. at the National Library of Medicine

See also Understanding Medical Terminology.

 
Published: May 21, 2012