- The clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division.
Definition from: MeSH via Unified Medical Language System at the National Library of Medicine
- The point or region on a chromosome to which the spindle attaches during mitosis and meiosis -- called also kinetochore.
Definition from: Merriam-Webster's Medical Dictionary by Merriam-Webster Inc.
- A centromere is a constricted region of a chromosome that separates it into a short arm (p) and a long arm (q). During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes. Following DNA replication, the chromosome consists of two identical structures called sister chromatids, which are joined at the centromere.
Definition from: Talking Glossary of Genetic Terms from the National Human Genome Research Institute
Related discussion in the Handbook
See also Understanding Medical Terminology.