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Predisposing mutation

Synonym(s)

  • susceptibility gene

Definition(s)

A gene mutation that increases an individual's susceptibility or predisposition to a certain disease or disorder. When such a mutation is inherited, development of symptoms is more likely but not certain.

Definition from: GeneTestsThis link leads to a site outside Genetics Home Reference. from the University of Washington and Children's Health System, Seattle

Related discussion in the Handbook

 
Published: September 2, 2008