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Genes in this gene family provide instructions for making molecules called small miscellaneous noncoding RNAs. Noncoding RNAs are a particular type of RNA, which is a chemical cousin of DNA.
The most common form of RNA (called messenger RNA) is considered protein-coding RNA, because it acts as the blueprint for making proteins. Noncoding RNAs, however, do not carry (encode) information for producing proteins, although they do have other important functions in cells.
There are several types of noncoding RNAs. For example, transfer RNAs help assemble protein building blocks (amino acids) into functioning proteins. Small interfering RNAs suppress the activity (expression) of specific genes. The genes in the small miscellaneous noncoding RNA family provide instructions for making RNA molecules that have not been classified into one of the other types. For example, the TERC gene provides instructions for making an RNA molecule that is involved in the maintenance of structures called telomeres, which are composed of repeated segments of DNA found at the ends of chromosomes.
The HUGO Gene Nomenclature Committee (HGNC) provides an index of gene families (http://www.genenames.org/cgi-bin/genefamilies/) and their member genes.
Genetics Home Reference summarizes the normal function and health implications of these members of the small miscellaneous ncRNAs gene family: RMRP and TERC.
Genetics Home Reference includes these conditions related to genes in the small miscellaneous ncRNAs gene family:
You may find the following resources about the small miscellaneous ncRNAs gene family helpful.
acids ; DNA ; gene ; messenger RNA ; molecule ; protein ; RNA
You may find definitions for these and many other terms in the Genetics Home Reference Glossary (/glossary).
These sources were used to develop the Genetics Home Reference summary for the small miscellaneous ncRNAs gene family.
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? (http://ghr.nlm.nih.gov/handbook/consult/findingprofessional) in the Handbook.