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Related Gene(s)

The HUGO Gene Nomenclature Committee (HGNC) provides an index of gene familiesThis link leads to a site outside Genetics Home Reference. and their member genes.

Genetics Home Reference summarizes the normal function and health implications of these genes in the SH2 domain containing gene family:

  • BTK: Bruton tyrosine kinase
  • CHN1: chimerin 1
  • JAK2: Janus kinase 2
  • PIK3R1: phosphoinositide-3-kinase regulatory subunit 1
  • PTPN11: protein tyrosine phosphatase, non-receptor type 11
  • RASA1: RAS p21 protein activator 1
  • SH2D1A: SH2 domain containing 1A
  • SH3BP2: SH3-domain binding protein 2
  • STAT3: signal transducer and activator of transcription 3 (acute-phase response factor)
  • STAT4: signal transducer and activator of transcription 4
  • ZAP70: zeta chain of T cell receptor associated protein kinase 70kDa
Reviewed: December 2013
Published: February 8, 2016