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ZNF365
Genes >

ZNF365

The information on this page was automatically extracted from online scientific databases.

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What is the official name of the ZNF365 gene?

The official name of this gene is “zinc finger protein 365.”

ZNF365 is the gene's official symbol. The ZNF365 gene is also known by other names, listed below.

Read more about gene names and symbols on the About page.

What is the normal function of the ZNF365 gene?

From Entrez GeneThis link leads to a site outside Genetics Home Reference.:

This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified. [provided by RefSeq, May 2010]

From UniProt (TALAN_HUMAN)This link leads to a site outside Genetics Home Reference.:

May play a role in uric acid excretion.

How are changes in the ZNF365 gene related to health conditions?

UniProt (TALAN_HUMAN)This link leads to a site outside Genetics Home Reference. provides the following information about the ZNF365 gene's known or predicted involvement in human disease.

Uric acid nephrolithiasis (UAN)[1]This link leads to a site outside Genetics Home Reference.: A form of nephrolithiasis, a common multifactorial disease characterized by stones formation in the kidney and urinary tract. Nephrolithiasis is due to supersaturation of the urine by stone-forming constituents, including calcium, oxalate and uric acid. Crystals or foreign bodies can act as nidi, upon which ions from the supersaturated urine form microscopic crystalline structures. Uric acid nephrolithiasis occurs when the urine becomes overly concentrated with uric acid and accounts for 20% of all stones. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Entrez GeneThis link leads to a site outside Genetics Home Reference. lists the following diseases or traits (phenotypes) known or believed to be associated with changes in the ZNF365 gene.
  • Nephrolithiasis, uric acid, susceptibility to[1]This link leads to a site outside Genetics Home Reference.
UniProt and Entrez Gene cite these articles in OMIM, a catalog designed for genetics professionals and researchers that provides detailed information about genetic conditions and genes.
 Article
Number		Main Topic
[1]605990This link leads to a site outside Genetics Home Reference.NEPHROLITHIASIS, URIC ACID, SUSCEPTIBILITY TO
607818This link leads to a site outside Genetics Home Reference.ZINC FINGER PROTEIN 365

Where is the ZNF365 gene located?

Cytogenetic Location: 10q21.2

Molecular Location on chromosome 10: base pairs 64,133,915 to 64,431,770

The ZNF365 gene is located on the long (q) arm of chromosome 10 at position 21.2.

The ZNF365 gene is located on the long (q) arm of chromosome 10 at position 21.2.

More precisely, the ZNF365 gene is located from base pair 64,133,915 to base pair 64,431,770 on chromosome 10.

See How do geneticists indicate the location of a gene? in the Handbook.

Where can I find additional information about ZNF365?

You may also be interested in these resources, which are designed for genetics professionals and researchers.

What other names do people use for the ZNF365 gene or gene products?

  • Su48
  • UAN
  • ZNF365D

See How are genetic conditions and genes named? in the Handbook.

Where can I find general information about genes?

The Handbook provides basic information about genetics in clear language.

These links provide additional genetics resources that may be useful.

What glossary definitions help with understanding ZNF365?

calcium ; excretion ; gene ; ions ; isoforms ; kidney ; mutation ; stone ; susceptibility ; uric acid

You may find definitions for these and many other terms in the Genetics Home Reference Glossary.

See also Understanding Medical Terminology.

 

The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.

 
Published: May 13, 2013