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Reviewed September 2010
What is the official name of the ZIC2 gene?
The official name of this gene is “Zic family member 2.”
ZIC2 is the gene's official symbol. The ZIC2 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the ZIC2 gene?
The ZIC2 gene provides instructions for making a protein that plays an important role in the development of the front part of the brain (forebrain). This protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity of certain genes. The ZIC2 protein regulates genes involved in both early and late stages of forebrain development.
How are changes in the ZIC2 gene related to health conditions?
Where is the ZIC2 gene located?
Cytogenetic Location: 13q32
Molecular Location on chromosome 13: base pairs 99,981,772 to 99,986,765
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The ZIC2 gene is located on the long (q) arm of chromosome 13 at position 32.
More precisely, the ZIC2 gene is located from base pair 99,981,772 to base pair 99,986,765 on chromosome 13.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about ZIC2?
You and your healthcare professional may find the following resources about ZIC2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the ZIC2 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding ZIC2?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (11 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.