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Reviewed November 2015
What is the official name of the TNXB gene?
The official name of this gene is “tenascin XB.”
TNXB is the gene's official symbol. The TNXB gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the TNXB gene?
The TNXB gene provides instructions for making a protein called tenascin-X. This protein plays an important role in organizing and maintaining the structure of tissues that support the body's muscles, joints, organs, and skin (connective tissues). In particular, studies suggest that it helps to regulate the production and assembly of certain types of collagen. Collagens are a family of proteins that strengthen and support connective tissues throughout the body. Tenascin-X is also involved in regulating the structure and stability of elastic fibers, which provide flexibility and stretchiness (elasticity) to connective tissues.
Does the TNXB gene share characteristics with other genes?
The TNXB gene belongs to a family of genes called fibronectin type III domain containing (fibronectin type III domain containing).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the TNXB gene related to health conditions?
Where is the TNXB gene located?
Cytogenetic Location: 6p21.3
Molecular Location on chromosome 6: base pairs 32,041,155 to 32,109,374
The TNXB gene is located on the short (p) arm of chromosome 6 at position 21.3.
More precisely, the TNXB gene is located from base pair 32,041,155 to base pair 32,109,374 on chromosome 6.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about TNXB?
You and your healthcare professional may find the following resources about TNXB helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the TNXB gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding TNXB?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (10 links)