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Reviewed November 2006
What is the official name of the TMC1 gene?
The official name of this gene is “transmembrane channel-like 1.”
TMC1 is the gene's official symbol. The TMC1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the TMC1 gene?
The TMC1 gene provides instructions for making a protein called transmembrane channel-like 1. This protein is found in the inner ear, but its function is not fully understood. Based on its location in the inner ear, the TMC1 protein probably plays a role in converting sound waves to nerve impulses, a critical process for normal hearing. Alternatively, the TMC1 protein may be involved in signalling processes that are important for the survival of cells in the inner ear.
How are changes in the TMC1 gene related to health conditions?
Where is the TMC1 gene located?
Cytogenetic Location: 9q21.12
Molecular Location on chromosome 9: base pairs 72,521,800 to 72,836,350
The TMC1 gene is located on the long (q) arm of chromosome 9 at position 21.12.
More precisely, the TMC1 gene is located from base pair 72,521,800 to base pair 72,836,350 on chromosome 9.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about TMC1?
You and your healthcare professional may find the following resources about TMC1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the TMC1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding TMC1?
acids ; amino acid ; asparagine ; aspartic acid ; autosomal ; autosomal dominant ; autosomal recessive ; cell ; channel ; expressed ; gene ; inheritance ; inherited ; mutation ; protein ; recessive ; transmembrane
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.