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Reviewed August 2015
What is the official name of the TAT gene?
The official name of this gene is “tyrosine aminotransferase.”
TAT is the gene's official symbol. The TAT gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the TAT gene?
The TAT gene provides instructions for making a liver enzyme called tyrosine aminotransferase. This enzyme is the first in a series of five enzymes that work to break down the amino acid tyrosine, a protein building block found in many foods. Specifically, tyrosine aminotransferase converts tyrosine into a byproduct called 4-hydroxyphenylpyruvate. Continuing the process, 4-hydroxyphenylpyruvate is further broken down and ultimately smaller molecules are produced that are either excreted by the kidneys or used to produce energy or make other substances in the body.
How are changes in the TAT gene related to health conditions?
Where is the TAT gene located?
Cytogenetic Location: 16q22.1
Molecular Location on chromosome 16: base pairs 71,566,851 to 71,577,095
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The TAT gene is located on the long (q) arm of chromosome 16 at position 22.1.
More precisely, the TAT gene is located from base pair 71,566,851 to base pair 71,577,095 on chromosome 16.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about TAT?
You and your healthcare professional may find the following resources about TAT helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the TAT gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding TAT?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (4 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.