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The information on this page was automatically extracted from online scientific databases.

What is the official name of the TAGAP gene?

The official name of this gene is “T-cell activation RhoGTPase activating protein.”

TAGAP is the gene's official symbol. The TAGAP gene is also known by other names, listed below.

Read more about gene names and symbols on the About page.

What is the normal function of the TAGAP gene?

From NCBI GeneThis link leads to a site outside Genetics Home Reference.:

This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

From UniProt (TAGAP_HUMAN)This link leads to a site outside Genetics Home Reference.:

May function as a GTPase-activating protein and may play important roles during T-cell activation.

How are changes in the TAGAP gene related to health conditions?

Genetics Home Reference provides information about rheumatoid arthritis, which is associated with changes in the TAGAP gene.
OMIM.orgThis link leads to a site outside Genetics Home Reference., a catalog designed for genetics professionals and researchers, provides the following information about the TAGAP gene and its association with health conditions.

Where is the TAGAP gene located?

Cytogenetic Location: 6q25.3

Molecular Location on chromosome 6: base pairs 159,034,468 to 159,045,152

(Homo sapiens Annotation Release 107, GRCh38.p2) (NCBIThis link leads to a site outside Genetics Home Reference.)

The TAGAP gene is located on the long (q) arm of chromosome 6 at position 25.3.

The TAGAP gene is located on the long (q) arm of chromosome 6 at position 25.3.

More precisely, the TAGAP gene is located from base pair 159,034,468 to base pair 159,045,152 on chromosome 6.

See How do geneticists indicate the location of a gene? in the Handbook.

Where can I find additional information about TAGAP?

You may also be interested in these resources, which are designed for genetics professionals and researchers.

What other names do people use for the TAGAP gene or gene products?

  • ARHGAP47
  • FKSG15
  • IDDM21
  • TAGAP1

Where can I find general information about genes?

The Handbook provides basic information about genetics in clear language.

These links provide additional genetics resources that may be useful.

What glossary definitions help with understanding TAGAP?

alternate splicing ; arthritis ; cell ; gene ; isoforms ; protein ; sclerosis ; splicing ; transcript

You may find definitions for these and many other terms in the Genetics Home Reference Glossary.

See also Understanding Medical Terminology.


The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.

Published: February 1, 2016