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Reviewed August 2013
What is the official name of the SOX9 gene?
The official name of this gene is “SRY box 9.”
SOX9 is the gene's official symbol. The SOX9 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SOX9 gene?
The SOX9 gene provides instructions for making a protein that plays a critical role during embryonic development. The SOX9 protein is especially important for the development of the skeleton and reproductive system. This protein attaches (binds) to specific regions of DNA and regulates the activity of other genes. On the basis of this action, the SOX9 protein is called a transcription factor.
Does the SOX9 gene share characteristics with other genes?
The SOX9 gene belongs to a family of genes called SOX (SRY (sex determining region Y)-boxes).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the SOX9 gene related to health conditions?
Genetics Home Reference provides information about Swyer syndrome, which is also associated with changes in the SOX9 gene.
Where is the SOX9 gene located?
Cytogenetic Location: 17q24.3
Molecular Location on chromosome 17: base pairs 72,121,020 to 72,126,420
The SOX9 gene is located on the long (q) arm of chromosome 17 at position 24.3.
More precisely, the SOX9 gene is located from base pair 72,121,020 to base pair 72,126,420 on chromosome 17.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SOX9?
You and your healthcare professional may find the following resources about SOX9 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SOX9 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SOX9?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (13 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.