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Reviewed January 2013
What is the official name of the SLC2A10 gene?
The official name of this gene is “solute carrier family 2 (facilitated glucose transporter), member 10.”
SLC2A10 is the gene's official symbol. The SLC2A10 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SLC2A10 gene?
The SLC2A10 gene provides instructions for making a protein called GLUT10. GLUT10 is classified as a glucose transporter; this type of protein moves the simple sugar glucose across cell membranes and helps maintain proper levels of glucose within cells. However, GLUT10 has some structural differences from other glucose transporters, and its role in the movement of glucose or other substances is unclear.
The level of GLUT10 appears to be involved in the regulation of a process called the transforming growth factor-beta (TGF-β) signaling pathway. This pathway is involved in cell growth and division (proliferation) and the process by which cells mature to carry out special functions (differentiation). The TGF-β signaling pathway is also involved in bone and blood vessel development and the formation of the extracellular matrix, an intricate lattice of proteins and other molecules that forms in the spaces between cells and defines the structure and properties of connective tissues. Connective tissue provides strength and flexibility to structures throughout the body, including blood vessels, skin, joints, and the gastrointestinal tract.
Studies indicate that GLUT10 may also be involved in the functioning of mitochondria, the energy-producing centers within cells.
Does the SLC2A10 gene share characteristics with other genes?
The SLC2A10 gene belongs to a family of genes called SLC (solute carriers).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the SLC2A10 gene related to health conditions?
Where is the SLC2A10 gene located?
Cytogenetic Location: 20q13.1
Molecular Location on chromosome 20: base pairs 46,708,347 to 46,736,347
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The SLC2A10 gene is located on the long (q) arm of chromosome 20 at position 13.1.
More precisely, the SLC2A10 gene is located from base pair 46,708,347 to base pair 46,736,347 on chromosome 20.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SLC2A10?
You and your healthcare professional may find the following resources about SLC2A10 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SLC2A10 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SLC2A10?
arteries ; artery ; atherosclerosis ; cardiovascular ; carrier ; cell ; connective tissue ; deficiency ; diabetes ; differentiation ; extracellular ; extracellular matrix ; gastrointestinal ; gene ; glucose ; growth factor ; hormone ; hyperglycemia ; insulin ; joint ; mitochondria ; peripheral ; proliferation ; protein ; simple sugar ; solute ; syndrome ; tissue ; tortuosity
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (11 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.