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Reviewed January 2014
What is the official name of the SLC19A3 gene?
The official name of this gene is “solute carrier family 19 (thiamine transporter), member 3.”
SLC19A3 is the gene's official symbol. The SLC19A3 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SLC19A3 gene?
The SLC19A3 gene provides instructions for making a protein called a thiamine transporter, which moves a vitamin called thiamine into cells. Thiamine, also known as vitamin B1, is obtained from the diet. It is involved in many cellular processes, and is necessary for proper functioning of the nervous system. Molecules made from thiamine are important in the breakdown of sugars and protein building blocks (amino acids). Thiamine is also involved in the production of certain chemicals that relay signals in the nervous system (neurotransmitters).
Does the SLC19A3 gene share characteristics with other genes?
The SLC19A3 gene belongs to a family of genes called SLC (solute carriers).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the SLC19A3 gene related to health conditions?
Where is the SLC19A3 gene located?
Cytogenetic Location: 2q37
Molecular Location on chromosome 2: base pairs 227,685,210 to 227,718,029
The SLC19A3 gene is located on the long (q) arm of chromosome 2 at position 37.
More precisely, the SLC19A3 gene is located from base pair 227,685,210 to base pair 227,718,029 on chromosome 2.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SLC19A3?
You and your healthcare professional may find the following resources about SLC19A3 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SLC19A3 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SLC19A3?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (8 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.