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Reviewed February 2008
What is the official name of the SLC17A5 gene?
The official name of this gene is “solute carrier family 17 (acidic sugar transporter), member 5.”
SLC17A5 is the gene's official symbol. The SLC17A5 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SLC17A5 gene?
The SLC17A5 gene provides instructions for producing a protein called sialin that is located mainly on the membranes of lysosomes, compartments in the cell that digest and recycle materials. Sialin moves a molecule called free sialic acid, which is produced when certain proteins and fats are broken down, out of the lysosomes to other parts of the cell. Free sialic acid means that the sialic acid is not attached (bound) to other molecules.
Researchers believe that sialin may also have other functions in brain cells, in addition to those associated with the lysosomes, but these additional functions are not well understood.
Does the SLC17A5 gene share characteristics with other genes?
The SLC17A5 gene belongs to a family of genes called SLC (solute carriers).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the SLC17A5 gene related to health conditions?
Where is the SLC17A5 gene located?
Cytogenetic Location: 6q13
Molecular Location on chromosome 6: base pairs 73,593,379 to 73,654,014
The SLC17A5 gene is located on the long (q) arm of chromosome 6 at position 13.
More precisely, the SLC17A5 gene is located from base pair 73,593,379 to base pair 73,654,014 on chromosome 6.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SLC17A5?
You and your healthcare professional may find the following resources about SLC17A5 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SLC17A5 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SLC17A5?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (7 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.