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Reviewed March 2014
What is the official name of the SKIV2L gene?
The official name of this gene is “superkiller viralicidic activity 2-like (S. cerevisiae).”
SKIV2L is the gene's official symbol. The SKIV2L gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SKIV2L gene?
The SKIV2L gene provides instructions for making a protein whose function has not been confirmed. Based on its similarity to a protein in other organisms, researchers speculate that the SKIV2L protein acts as part of a group of proteins called the SKI complex. This complex is thought to be necessary for the function of another large protein complex known as the cytosolic exosome. Within cells, the cytosolic exosome helps to recognize and break down excess or abnormal messenger RNA (mRNA) molecules. mRNA is a chemical cousin of DNA that serves as the genetic blueprint for protein production. Studies suggest that the cytosolic exosome's role in getting rid of excess and abnormal mRNA is important for cell growth.
How are changes in the SKIV2L gene related to health conditions?
Where is the SKIV2L gene located?
Cytogenetic Location: 6p21
Molecular Location on chromosome 6: base pairs 31,958,803 to 31,969,754
The SKIV2L gene is located on the short (p) arm of chromosome 6 at position 21.
More precisely, the SKIV2L gene is located from base pair 31,958,803 to base pair 31,969,754 on chromosome 6.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SKIV2L?
You and your healthcare professional may find the following resources about SKIV2L helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SKIV2L gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SKIV2L?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (4 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.