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Reviewed July 2010
What is the official name of the SAMHD1 gene?
The official name of this gene is “SAM domain and HD domain 1.”
SAMHD1 is the gene's official symbol. The SAMHD1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the SAMHD1 gene?
The SAMHD1 gene provides instructions for making a protein whose function is not well understood. The SAMHD1 protein is believed to be involved in the immune system, including the inflammatory process and response to viral infections.
How are changes in the SAMHD1 gene related to health conditions?
Where is the SAMHD1 gene located?
Cytogenetic Location: 20pter-q12
Molecular Location on chromosome 20: base pairs 36,891,824 to 36,951,843
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The SAMHD1 gene is located on chromosome 20 between the short (p) arm at the end (terminus) of the arm and the long (q) arm at position 12.
More precisely, the SAMHD1 gene is located from base pair 36,891,824 to base pair 36,951,843 on chromosome 20.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about SAMHD1?
You and your healthcare professional may find the following resources about SAMHD1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the SAMHD1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding SAMHD1?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (6 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.