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Reviewed January 2010
What is the official name of the RAB7A gene?
The official name of this gene is “RAB7A, member RAS oncogene family.”
RAB7A is the gene's official symbol. The RAB7A gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the RAB7A gene?
The RAB7A gene provides instructions for making a protein that is involved in endocytosis, a process that brings substances into the cell. During endocytosis, the cell membrane folds around a substance outside the cell (such as a protein) to form a sac-like structure called a vesicle. The vesicle is drawn into the cell and is pinched off from the cell membrane. The RAB7A protein plays a role in vesicle trafficking, which is the movement of these vesicles within the cell.
Does the RAB7A gene share characteristics with other genes?
The RAB7A gene belongs to a family of genes called RAB (RAB, member RAS oncogene family).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the RAB7A gene related to health conditions?
Where is the RAB7A gene located?
Cytogenetic Location: 3q21.3
Molecular Location on chromosome 3: base pairs 128,726,136 to 128,814,798
The RAB7A gene is located on the long (q) arm of chromosome 3 at position 21.3.
More precisely, the RAB7A gene is located from base pair 128,726,136 to base pair 128,814,798 on chromosome 3.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about RAB7A?
You and your healthcare professional may find the following resources about RAB7A helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the RAB7A gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding RAB7A?
acids ; axons ; cell ; cell membrane ; endocytosis ; gene ; nervous system ; neurotransmitters ; oncogene ; peripheral ; peripheral nervous system ; protein ; RAS ; RAS oncogene ; sensory cells ; vesicle
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (11 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.