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Reviewed November 2012
What is the official name of the PDCD10 gene?
The official name of this gene is “programmed cell death 10.”
PDCD10 is the gene's official symbol. The PDCD10 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the PDCD10 gene?
The PDCD10 gene (also known as CCM3) provides instructions for making a protein that appears to play a role in the structure of blood vessels. While the exact function of the PDCD10 protein is unclear, studies suggest that it works with other proteins to help strengthen the interactions between cells and limit leakage from blood vessels. This protein is also thought to be involved in pathways that signal cells to self-destruct (undergo apoptosis) when they have completed a certain number of cell divisions or accumulated errors in their DNA.
How are changes in the PDCD10 gene related to health conditions?
Where is the PDCD10 gene located?
Cytogenetic Location: 3q26.1
Molecular Location on chromosome 3: base pairs 167,683,735 to 167,735,422
(Homo sapiens Annotation Release 107, GRCh38.p2) (
The PDCD10 gene is located on the long (q) arm of chromosome 3 at position 26.1.
More precisely, the PDCD10 gene is located from base pair 167,683,735 to base pair 167,735,422 on chromosome 3.
See How do geneticists indicate the location of a gene? in the Handbook.
Where can I find additional information about PDCD10?
You and your healthcare professional may find the following resources about PDCD10 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the PDCD10 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding PDCD10?
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.