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Reviewed November 2006
What is the official name of the MT-RNR1 gene?
The official name of this gene is “mitochondrially encoded 12S RNA.”
MT-RNR1 is the gene's official symbol. The MT-RNR1 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MT-RNR1 gene?
The MT-RNR1 gene provides instructions for making a particular type of RNA, a molecule that is a chemical cousin of DNA. This type of RNA, known as ribosomal RNA (rRNA), is involved in the assembly of proteins within cells.
The MT-RNR1 gene provides instructions for a specific form of ribosomal RNA called 12S RNA, which is present only in cellular structures called mitochondria. These structures convert energy from food into a form that cells can use. Through a process called oxidative phosphorylation, mitochondria use oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source. 12S RNA molecules help assemble protein building blocks (amino acids) into the functioning proteins that carry out oxidative phosphorylation.
How are changes in the MT-RNR1 gene related to health conditions?
Where is the MT-RNR1 gene located?
The MT-RNR1 gene is located in mitochondrial DNA.
Molecular Location in mitochondrial DNA: base pairs 648 to 1,601
Where can I find additional information about MT-RNR1?
You and your healthcare professional may find the following resources about MT-RNR1 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MT-RNR1 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MT-RNR1?
acids ; adenosine triphosphate ; aminoglycoside ; antibiotics ; apoptosis ; ATP ; bacteria ; cell ; chronic ; DNA ; gene ; mitochondria ; molecule ; ototoxicity ; oxidative phosphorylation ; oxygen ; pharmacogenomics ; phosphorylation ; protein ; reactive oxygen species ; ribosomal RNA ; RNA ; tuberculosis
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (9 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.