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Reviewed October 2011
What is the official name of the MT-ATP6 gene?
The official name of this gene is “mitochondrially encoded ATP synthase 6.”
MT-ATP6 is the gene's official symbol. The MT-ATP6 gene is also known by other names, listed below.
Read more about gene names and symbols on the About page.
What is the normal function of the MT-ATP6 gene?
The MT-ATP6 gene provides information for making a protein that is essential for normal mitochondrial function. Mitochondria are structures within cells that convert the energy from food into a form that cells can use. These cellular structures produce energy through a process called oxidative phosphorylation, which uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source.
The MT-ATP6 protein forms one part (subunit) of a large enzyme called ATP synthase. This enzyme, which is also known as complex V, is responsible for the final step of oxidative phosphorylation. Specifically, one segment of ATP synthase allows positively charged particles, called protons, to flow across a specialized membrane inside mitochondria. Another segment of the enzyme uses the energy created by this proton flow to convert a molecule called adenosine diphosphate (ADP) to ATP.
Does the MT-ATP6 gene share characteristics with other genes?
The MT-ATP6 gene belongs to a family of genes called mitochondrial respiratory chain complex (mitochondrial respiratory chain complex).
A gene family is a group of genes that share important characteristics. Classifying individual genes into families helps researchers describe how genes are related to each other. For more information, see What are gene families? in the Handbook.
How are changes in the MT-ATP6 gene related to health conditions?
Where is the MT-ATP6 gene located?
The MT-ATP6 gene is located in mitochondrial DNA.
Molecular Location in mitochondrial DNA: base pairs 8,526 to 9,206
Where can I find additional information about MT-ATP6?
You and your healthcare professional may find the following resources about MT-ATP6 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
What other names do people use for the MT-ATP6 gene or gene products?
See How are genetic conditions and genes named? in the Handbook.
Where can I find general information about genes?
The Handbook provides basic information about genetics in clear language.
These links provide additional genetics resources that may be useful.
What glossary definitions help with understanding MT-ATP6?
adenosine diphosphate ; adenosine triphosphate ; ADP ; ataxia ; ATP ; bilateral ; cell ; charged particles ; DNA ; enzyme ; familial ; gene ; guanine ; hypotonia ; microcephaly ; mitochondria ; molecule ; muscle tone ; mutation ; necrosis ; neuropathy ; nucleotide ; oxidative phosphorylation ; oxygen ; phosphorylation ; protein ; proton ; spectrum ; striatal ; subunit ; syndrome ; thymine
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
See also Understanding Medical Terminology.
References (10 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.